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| 27 Feb 2024 | AGIOAgios Pharmaceuticals Inc | David P Schenkein Director | Option | 69,329 | $31.64 | $2,193,570 27 Feb 2024 | 180,325 | ↗ |
| 23 Feb 2024 | AGIOAgios Pharmaceuticals Inc | David P Schenkein Director | Option | 68,142 | $31.64 | $2,156,013 23 Feb 2024 | 143,265 | ↗ |
| 21 Jun 2023 | AGIOAgios Pharmaceuticals Inc | David P Schenkein Director | Option | 4,975 | $26.98 | $134,226 21 Jun 2023 | 122,854 | ↗ |
| 3 Apr 2023 | AGIOAgios Pharmaceuticals Inc | David P Schenkein Director | Option | 16,363 | $9.05 | $148,085 3 Apr 2023 | 134,242 | ↗ |
| 27 Mar 2023 | AGIOAgios Pharmaceuticals Inc | David P Schenkein Director | Option | 20,000 | $9.05 | $181,000 27 Mar 2023 | 137,879 | ↗ |
| 13 Mar 2023 | AGIOAgios Pharmaceuticals Inc | David P Schenkein Director | Option | 20,000 | $9.05 | $181,000 13 Mar 2023 | 137,879 | ↗ |
| 27 Feb 2023 | AGIOAgios Pharmaceuticals Inc | David P Schenkein Director | Option | 20,000 | $9.05 | $181,000 27 Feb 2023 | 137,879 | ↗ |
| 13 Feb 2023 | AGIOAgios Pharmaceuticals Inc | David P Schenkein Director | Option | 20,000 | $9.05 | $181,000 13 Feb 2023 | 137,879 | ↗ |
| 30 Jan 2023 | AGIOAgios Pharmaceuticals Inc | David P Schenkein Director | Option | 20,000 | $9.05 | $181,000 30 Jan 2023 | 137,879 | ↗ |
| 17 Jan 2023 | AGIOAgios Pharmaceuticals Inc | David P Schenkein Director | Option | 20,000 | $9.05 | $181,000 17 Jan 2023 | 137,879 | ↗ |
| 20 May 2022 | AGIOAgios Pharmaceuticals Inc | David P Schenkein Director | Option | 1,585 | $21.10 | $33,444 20 May 2022 | 117,879 | ↗ |
| 22 Feb 2022 | AGIOAgios Pharmaceuticals Inc | David P Schenkein Director | Option | 2,775 | $28.86 | $80,087 22 Feb 2022 | 117,052 | ↗ |
| 28 May 2021 | AGIOAgios Pharmaceuticals Inc | David P Schenkein Director | Option | 1,686 | $55.78 | $94,045 28 May 2021 | 114,277 | ↗ |
| 22 Feb 2021 | AGIOAgios Pharmaceuticals Inc | David P Schenkein Director | Option | 2,774 | $53.84 | $149,352 22 Feb 2021 | 113,412 | ↗ |
| 16 Feb 2021 | AGIOAgios Pharmaceuticals Inc | David P Schenkein Director | Option | 8,125 | $54.37 | $441,756 16 Feb 2021 | 113,178 | ↗ |
| 22 Feb 2020 | AGIOAgios Pharmaceuticals Inc | David P Schenkein Director | Option | 2,775 | $53.11 | $147,380 22 Feb 2020 | 105,933 | ↗ |
| 16 Feb 2020 | AGIOAgios Pharmaceuticals Inc | David P Schenkein Director | Option | 8,125 | $51.51 | $418,519 16 Feb 2020 | 105,692 | ↗ |
| 13 Nov 2019 | AGIOAgios Pharmaceuticals Inc | David P Schenkein Director | Buy | 8,064 | $31.00 | $249,984 13 Nov 2019 | 97,567 | ↗ |
| 10 Sep 2018 | AGIOAgios Pharmaceuticals Inc | David P Schenkein Director | Option | 8,730 | $31.64 | $276,217 10 Sep 2018 | 83,849 | ↗ |
| 5 Sep 2018 | AGIOAgios Pharmaceuticals Inc | David P Schenkein Director | Option | 75,119 | $3.32 | $249,395 5 Sep 2018 | 75,119 | ↗ |
| 1 Jun 2018 | AGIOAgios Pharmaceuticals Inc | David P Schenkein Director | Option | 13,000 | $0.48 | $6,240 1 Jun 2018 | 13,000 | ↗ |
| 30 May 2018 | AGIOAgios Pharmaceuticals Inc | David P Schenkein Director | Option | 45,626 | $0.39 | $17,794 30 May 2018 | 45,626 | ↗ |
| 23 May 2018 | AGIOAgios Pharmaceuticals Inc | David P Schenkein Director | Option | 49,374 | $0.30 | $14,812 23 May 2018 | 49,374 | ↗ |
| 1 May 2018 | AGIOAgios Pharmaceuticals Inc | David P Schenkein Director | Option | 13,000 | $0.30 | $3,900 1 May 2018 | 13,000 | ↗ |
| 2 Apr 2018 | AGIOAgios Pharmaceuticals Inc | David P Schenkein Director | Option | 13,000 | $0.30 | $3,900 2 Apr 2018 | 13,000 | ↗ |
| 1 Mar 2018 | AGIOAgios Pharmaceuticals Inc | David P Schenkein Director | Option | 13,000 | $0.30 | $3,900 1 Mar 2018 | 13,000 | ↗ |
| 1 Feb 2018 | AGIOAgios Pharmaceuticals Inc | David P Schenkein Director | Option | 13,000 | $0.30 | $3,900 1 Feb 2018 | 13,000 | ↗ |
| 26 Jan 2018 | AGIOAgios Pharmaceuticals Inc | David P Schenkein Director | Option | 23,572 | $0.30 | $7,072 26 Jan 2018 | 23,572 | ↗ |
| 24 Jan 2018 | AGIOAgios Pharmaceuticals Inc | David P Schenkein Director | Option | 20 | $0.30 | $6 24 Jan 2018 | 20 | ↗ |
| 23 Jan 2018 | AGIOAgios Pharmaceuticals Inc | David P Schenkein Director | Option | 46,408 | $0.30 | $13,922 23 Jan 2018 | 13,533 | ↗ |
| 16 Jan 2018 | AGIOAgios Pharmaceuticals Inc | David P Schenkein Director | Option | 53,000 | $0.30 | $15,900 16 Jan 2018 | 53,000 | ↗ |
| 1 Dec 2017 | AGIOAgios Pharmaceuticals Inc | David P Schenkein Director | Option | 6,000 | $0.30 | $1,800 1 Dec 2017 | 6,000 | ↗ |
| 1 Nov 2017 | AGIOAgios Pharmaceuticals Inc | David P Schenkein Director | Option | 6,000 | $0.30 | $1,800 1 Nov 2017 | 6,000 | ↗ |
| 4 Oct 2017 | AGIOAgios Pharmaceuticals Inc | David P Schenkein Director | Option | 80,000 | $0.30 | $24,000 4 Oct 2017 | 80,000 | ↗ |
| 2 Oct 2017 | AGIOAgios Pharmaceuticals Inc | David P Schenkein Director | Option | 6,000 | $0.30 | $1,800 2 Oct 2017 | 6,000 | ↗ |
| 18 Sep 2017 | AGIOAgios Pharmaceuticals Inc | David P Schenkein Director | Option | 35,000 | $0.30 | $10,500 18 Sep 2017 | 35,000 | ↗ |
| 1 Sep 2017 | AGIOAgios Pharmaceuticals Inc | David P Schenkein Director | Option | 6,000 | $0.30 | $1,800 1 Sep 2017 | 6,000 | ↗ |
| 1 Aug 2017 | AGIOAgios Pharmaceuticals Inc | David P Schenkein Director | Option | 27,000 | $0.30 | $8,100 1 Aug 2017 | 24,000 | ↗ |
| 3 Jul 2017 | AGIOAgios Pharmaceuticals Inc | David P Schenkein Director | Option | 3,000 | $0.30 | $900 3 Jul 2017 | 3,000 | ↗ |
| 6 Jun 2017 | AGIOAgios Pharmaceuticals Inc | David P Schenkein Director | Option | 3,000 | $0.30 | $900 6 Jun 2017 | 1,900 | ↗ |
| 1 May 2017 | AGIOAgios Pharmaceuticals Inc | David P Schenkein Director | Option | 3,000 | $0.30 | $900 1 May 2017 | 3,000 | ↗ |
| 3 Apr 2017 | AGIOAgios Pharmaceuticals Inc | David P Schenkein Director | Option | 3,000 | $0.30 | $900 3 Apr 2017 | 3,000 | ↗ |
| 1 Mar 2017 | AGIOAgios Pharmaceuticals Inc | David P Schenkein Director | Option | 3,000 | $0.30 | $900 1 Mar 2017 | 3,000 | ↗ |
| 16 Feb 2017 | AGIOAgios Pharmaceuticals Inc | David P Schenkein Director | Option | 6,000 | $0.30 | $1,800 16 Feb 2017 | 6,000 | ↗ |
| 7 Jan 2016 | AGIOAgios Pharmaceuticals Inc | David P Schenkein Director | Option | 20,000 | $0.30 | $6,000 7 Jan 2016 | 272,272 | ↗ |
| 4 Jan 2016 | AGIOAgios Pharmaceuticals Inc | David P Schenkein Director | Option | 20,000 | $0.30 | $6,000 4 Jan 2016 | 252,272 | ↗ |
| 27 Oct 2015 | AGIOAgios Pharmaceuticals Inc | David P Schenkein Director | Option | 4,000 | $31.64 | $126,560 27 Oct 2015 | 236,272 | ↗ |
| 3 Aug 2015 | AGIOAgios Pharmaceuticals Inc | David P Schenkein Director | Option | 8,000 | $28.89 | $231,120 3 Aug 2015 | 240,272 | ↗ |
| 1 Jun 2015 | AGIOAgios Pharmaceuticals Inc | David P Schenkein Director | Sale | 13,000 | $120.67 | $1,568,710 1 Jun 2015 | 232,272 | ↗ |
| 11 May 2015 | AGIOAgios Pharmaceuticals Inc | David P Schenkein Director | Sale | 5,200 | $110.02 | $572,104 11 May 2015 | 94,701 | ↗ |
| 7 May 2015 | AGIOAgios Pharmaceuticals Inc | David P Schenkein Director | Option | 10,000 | $0.30 | $3,000 7 May 2015 | 241,372 | ↗ |
| 1 May 2015 | AGIOAgios Pharmaceuticals Inc | David P Schenkein Director | Sale | 3,900 | $93.63 | $365,157 1 May 2015 | 231,372 | ↗ |
| 13 Apr 2015 | AGIOAgios Pharmaceuticals Inc | David P Schenkein Director | Sale | 3,900 | $100.03 | $390,117 13 Apr 2015 | 101,201 | ↗ |
| 1 Apr 2015 | AGIOAgios Pharmaceuticals Inc | David P Schenkein Director | Sale | 3,900 | $92.54 | $360,906 1 Apr 2015 | 237,872 | ↗ |
| 12 Mar 2015 | AGIOAgios Pharmaceuticals Inc | David P Schenkein Director | Sale | 8,929 | $120.05 | $1,071,926 12 Mar 2015 | 85,582 | ↗ |
| 5 Mar 2015 | AGIOAgios Pharmaceuticals Inc | David P Schenkein Director | Sale | 2,600 | $110.16 | $286,416 5 Mar 2015 | 102,501 | ↗ |
| 27 Feb 2015 | AGIOAgios Pharmaceuticals Inc | David P Schenkein Director | Option | 25,000 | $0.30 | $7,500 27 Feb 2015 | 248,272 | ↗ |
| 11 Feb 2015 | AGIOAgios Pharmaceuticals Inc | David P Schenkein Director | Sale | 1,471 | $120.22 | $176,844 11 Feb 2015 | 106,401 | ↗ |
| 2 Feb 2015 | AGIOAgios Pharmaceuticals Inc | David P Schenkein Director | Sale | 10,400 | $114.31 | $1,188,824 2 Feb 2015 | 107,872 | ↗ |
| 2 Jan 2015 | AGIOAgios Pharmaceuticals Inc | David P Schenkein Director | Sale | 13,000 | $110.08 | $1,431,040 2 Jan 2015 | 111,772 | ↗ |
| 1 Dec 2014 | AGIOAgios Pharmaceuticals Inc | David P Schenkein Director | Sale | 13,000 | $97.03 | $1,261,390 1 Dec 2014 | 118,272 | ↗ |
| 3 Nov 2014 | AGIOAgios Pharmaceuticals Inc | David P Schenkein Director | Sale | 13,000 | $81.71 | $1,062,230 3 Nov 2014 | 124,772 | ↗ |
| 1 Oct 2014 | AGIOAgios Pharmaceuticals Inc | David P Schenkein Director | Sale | 13,000 | $60.07 | $780,910 1 Oct 2014 | 131,272 | ↗ |
| 26 Sep 2014 | AGIOAgios Pharmaceuticals Inc | David P Schenkein Director | Sale | 60,000 | $62.68 | $3,760,800 26 Sep 2014 | 137,772 | ↗ |
| 2 Sep 2014 | AGIOAgios Pharmaceuticals Inc | David P Schenkein Director | Sale | 13,000 | $46.30 | $601,900 2 Sep 2014 | 167,772 | ↗ |
| 11 Aug 2014 | AGIOAgios Pharmaceuticals Inc | David P Schenkein Director | Sale | 4,530 | $40.17 | $181,970 11 Aug 2014 | 174,272 | ↗ |
| 1 Aug 2014 | AGIOAgios Pharmaceuticals Inc | David P Schenkein Director | Sale | 8,470 | $39.17 | $331,770 1 Aug 2014 | 176,537 | ↗ |
| 1 Jul 2014 | AGIOAgios Pharmaceuticals Inc | David P Schenkein Director | Sale | 13,000 | $46.52 | $604,760 1 Jul 2014 | 180,772 | ↗ |
| 25 Mar 2014 | AGIOAgios Pharmaceuticals Inc | David P Schenkein Director | Option | 25,000 | $0.30 | $7,500 25 Mar 2014 | 266,272 | ↗ |
| 10 Mar 2014 | AGIOAgios Pharmaceuticals Inc | David P Schenkein Director | Option | 54,000 | $0.30 | $16,200 10 Mar 2014 | 241,272 | ↗ |
| 1 Jun 2021 | DNLIDenali Therapeutics Inc | David P Schenkein Director | Option | 3,253 | $61.59 | $200,352 1 Jun 2021 | 3,253 | ↗ |
| 21 Dec 2020 | DNLIDenali Therapeutics Inc | David P Schenkein Director | Sale | 30,000 | $90.05 | $2,701,500 21 Dec 2020 | 26,232 | ↗ |
| 12 Nov 2020 | DNLIDenali Therapeutics Inc | David P Schenkein Director | Sale | 30,000 | $70.05 | $2,101,500 12 Nov 2020 | 25,000 | ↗ |
| 10 Nov 2020 | DNLIDenali Therapeutics Inc | David P Schenkein Director | Sale | 10,000 | $60.03 | $600,300 10 Nov 2020 | 55,000 | ↗ |
| 4 Nov 2020 | DNLIDenali Therapeutics Inc | David P Schenkein Director | Sale | 10,000 | $50.18 | $501,800 4 Nov 2020 | 65,000 | ↗ |
| 31 Aug 2017 | BLUEBluebird bio Inc | David P Schenkein | Option | 2,000 | $8.16 | $16,320 31 Aug 2017 | 5,176 | ↗ |
| 1 Mar 2017 | BLUEBluebird bio Inc | David P Schenkein | Option | 5,000 | $8.16 | $40,800 1 Mar 2017 | 7,176 | ↗ |
| 1 Mar 2017 | BLUEBluebird bio Inc | David P Schenkein | Option | 5,000 | $8.16 | $40,800 1 Mar 2017 | 7,176 | ↗ |
| 19 Dec 2014 | BLUEBluebird bio Inc | David P Schenkein | Buy | 1,176 | $85.00 | $99,960 19 Dec 2014 | 1,176 | ↗ |
